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Microbiology with Diseases by Body System, 3e (Bauman)
Chapter 2 The Chemistry of Microbiology
2.1 Multiple-Choice Questions
1) Which of the following is a particle that is found in the nucleus of an atom and has no
electrical charge?
A) electron
B) neutron
C) element
D) proton
E) isotope
Answer: B
Bloom’s Rank: Knowledge
Section: Atoms
2) An atom of carbon that has six protons and seven neutrons is an example of a(n)
A) isotope.
B) radioactive isotope.
C) molecule.
D) compound.
E) dalton.
Answer: A
Bloom’s Rank: Application
Section: Atoms
3) An atom is electrically neutral when
A) the number of electrons equals the number of neutrons.
B) the numbers of its protons, electrons, and neutrons are all equal.
C) it has no extra electrons in its valence shell.
D) the number of protons equals the number of neutrons.
E) the number of electrons equals the number of protons.
Answer: E
Bloom’s Rank: Application
Section: Atoms
4) Which parts of the atoms interact in a chemical reaction?
A) protons
B) neutrons
C) ions
D) electrons
E) isotopes
Answer: D
Bloom’s Rank: Comprehension
Section: Atoms
2
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5) All of the following are associated with atomic structure EXCEPT
A) valence.
B) dalton.
C) monomer.
D) electron shell.
E) neutron.
Answer: C
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
6) The valence of an atom represents its
A) ability to interact with other atoms.
B) electronegativity.
C) radioactivity.
D) ability to attract electrons.
E) ability to interact with water.
Answer: A
Bloom’s Rank: Comprehension
Section: Atoms
7) The type(s) of bond produced when atoms share electrons equally is/are
A) a nonpolar covalent bond.
B) a hydrogen bond.
C) an ionic bond.
D) a polar covalent bond.
E) polar covalent and ionic bonds.
Answer: A
Bloom’s Rank: Comprehension
Section: Chemical Bonds
8) The type(s) of bond produced when atoms with significantly different electronegativities share
electrons is/are
A) a nonpolar covalent bond.
B) a polar covalent bond.
C) an ionic bond.
D) a hydrogen bond.
E) nonpolar covalent and ionic bonds.
Answer: B
Bloom’s Rank: Comprehension
Section: Chemical Bonds
3
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9) Which of the following types of chemical bonds do carbon atoms generally NOT form?
A) nonpolar covalent bonds
B) polar covalent bonds
C) ionic bonds
D) hydrogen bonds
E) both ionic and hydrogen bonds
Answer: E
Bloom’s Rank: Application
Section: Chemical Bonds
10) All of the following are associated with ionic bonds EXCEPT
A) cations.
B) radioactivity.
C) electrolytes.
D) salts.
E) anions.
Answer: B
Bloom’s Rank: Comprehension
Section: Chemical Bonds
11) Which of the following is an INCORRECT pairing?
A) electrolytes: anions
B) synthesis: endothermic
C) hydrolysis: hydrogen bonds
D) catabolism: exothermic
E) dehydration: anabolism
Answer: C
Bloom’s Rank: Application
Section: Chemical Reactions
12) Compounds that readily dissociate in water are
A) nonpolar.
B) ionic.
C) polar.
D) either polar or ionic.
E) never polar or ionic.
Answer: D
Bloom’s Rank: Comprehension
Section: Water, Acids, Bases, and Salts
4
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13) Which of the following is a property of water?
A) It has a high capacity for heat.
B) It is not a common reactant in metabolic reactions.
C) It is not a good solvent.
D) It is liquid in a very narrow temperature range.
E) It is a non-polar molecule.
Answer: A
Bloom’s Rank: Comprehension
Section: Water, Acids, Bases, and Salts
14) An acid dissociates in water to release
A) hydrogen ion(s).
B) cation(s).
C) hydroxyl group(s).
D) anion(s).
E) both anions and hydrogen ions.
Answer: E
Bloom’s Rank: Knowledge
Section: Water, Acids, Bases, and Salts
15) The reverse of a dehydration synthesis reaction is a(n) __________ reaction.
A) anabolic
B) exchange
C) hydrolytic
D) endothermic
E) metabolic
Answer: C
Bloom’s Rank: Knowledge
Section: Chemical Reactions
16) Which pH would be alkaline?
A) 7.0
B) 8.0
C) 4.0
D) 1.5
E) 6.5
Answer: B
Bloom’s Rank: Knowledge
Section: Water, Acids, Bases, and Salts
5
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17) Which of the following is NOT a characteristic of saturated fats?
A) They are usually solid at room temperature.
B) They contain at least one double bond.
C) They are found in animals.
D) Their fatty acids pack tightly together.
E) They are a form of stored energy.
Answer: B
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
18) Which of the following is NOT a characteristic of phospholipids?
A) They are found in cellular membranes.
B) They can form micelles and bilayers.
C) They contain fatty acids that associate with water.
D) They contain a hydrophilic phosphate “head.”
E) They contain two fatty acids and a phosphate functional group.
Answer: C
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
19) Organisms use carbohydrates in all of the following ways EXCEPT
A) as a component of cell walls.
B) as a long-term energy source.
C) as a short-term energy source.
D) to keep membranes flexible at low temperatures.
E) as a building block of DNA and RNA molecules.
Answer: D
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
20) Fats, proteins, and complex carbohydrates are all produced by
A) hydrolytic reactions.
B) dehydration synthesis.
C) exchange reactions.
D) hydrogen bonding.
E) catabolic reactions.
Answer: B
Bloom’s Rank: Application
Section: Organic Macromolecules
6
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21) Which of the following is an example of a polysaccharide?
A) glycogen
B) glucose
C) fructose
D) deoxyribose
E) sucrose
Answer: A
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
22) Which of the following statements about proteins is FALSE?
A) They are composed of amino acids.
B) They have multiple levels of structural organization.
C) They can be hydrophobic, hydrophilic, or both.
D) Their primary function is energy storage.
E) They are formed by dehydration synthesis reactions.
Answer: D
Bloom’s Rank: Application
Section: Organic Macromolecules
23) All of the following are components of an amino acid EXCEPT
A) a carboxyl group.
B) a pentose group.
C) an amino group.
D) an α-carbon.
E) an R group.
Answer: B
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
24) Which of the following is found in nucleic acids?
A) ionic bonds
B) peptide bonds
C) purines
D) ß-sheets
E) disulfide bridges
Answer: C
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
7
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25) Hydrogen bonds are found in all of the following EXCEPT
A) between phosphates in ATP.
B) in α-helices.
C) between water molecules.
D) in the DNA double helix between nucleotides.
E) between the R groups of amino acids in proteins.
Answer: A
Bloom’s Rank: Application
Section: Organic Macromolecules
26) Tertiary and quaternary structure of proteins involves __________ bonds.
A) hydrogen
B) ionic
C) polar covalent
D) nonpolar covalent
E) ionic, hydrogen, polar, and nonpolar covalent
Answer: E
Bloom’s Rank: Application
Section: Organic Macromolecules
27) Which of the following are examples of pyrimidines?
A) uracil and adenine
B) cytosine and guanine
C) thymine and adenine
D) thymine and guanine
E) cytosine and thymine
Answer: E
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
28) All of the following bases are found in RNA molecules EXCEPT
A) adenine.
B) thymine.
C) uracil.
D) cytosine.
E) guanine.
Answer: B
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
8
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29) The “spine” of the DNA molecule is composed of
A) amino acids.
B) pentoses.
C) phosphates.
D) nitrogenous bases.
E) alternating phosphates and pentoses.
Answer: E
Bloom’s Rank: Application
Section: Organic Macromolecules
30) Which of the following would NOT normally be found as a component of a cell’s nucleic
acids?
A) adenine deoxyribonucleotides
B) thymine deoxyribonucleotides
C) uracil deoxyribonucleotides
D) cytosine ribonucleotides
E) adenine ribonucleotides
Answer: C
Bloom’s Rank: Application
Section: Organic Macromolecules
31) All of the following are associated with ATP molecules EXCEPT
A) a long-term energy supply.
B) high-energy bonds.
C) a recyclable energy supply.
D) formation of coenzymes.
E) three phosphate groups.
Answer: A
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
32) Which of the following statements concerning nucleic acids is FALSE?
A) Nucleic acid strands are held together by hydrogen bonds between complementary bases.
B) Not all DNA is double stranded.
C) Some viruses have DNA as their genomes.
D) The nucleic acid polymer is composed of peptide bonds.
E) Cytosine is found in all nucleic acid molecules.
Answer: D
Bloom’s Rank: Application
Section: Organic Macromolecules
9
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33) Which of the following is an INCORRECT pairing?
A) primary structure: amino acid sequence
B) secondary structure: disulfide bridges
C) tertiary structure: covalent bonds
D) quaternary structure: two or more polypeptides
E) secondary structure: β-pleated sheets
Answer: B
Bloom’s Rank: Application
Section: Organic Macromolecules
34) Proteins contain both acidic and basic R groups, and can therefore function as
A) energy storage macromolecules.
B) structural macromolecules.
C) buffers.
D) catalysts.
E) genetic material.
Answer: C
Bloom’s Rank: Application
Section: Organic Macromolecules
35) An increase in the pH of a solution by 2 whole numbers represents a change in the number of
hydrogen ions by what factor?
A) 2
B) 20
C) 1000
D) 10
E) 100
Answer: E
Bloom’s Rank: Comprehension
Section: Water, Acids, Bases, and Salts
36) Plant cell walls are composed of __________ held together by __________.
A) polysaccharides, hydrogen bonds
B) amino acids, peptide bonds
C) disaccharides, hydrophobic interactions
D) fatty acids, polar covalent bonds
E) peptidoglycan, ionic bonds
Answer: A
Bloom’s Rank: Application
Section: Organic Macromolecules
10
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37) The presence of __________ in the cell wall of a microbe causes it to be resistant to drying.
A) fats
B) phospholipids
C) sterols
D) glycolipids
E) waxes
Answer: E
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
38) Some __________ are used as hormones.
A) phospholipids
B) waxes
C) steroids
D) ions
E) polyunsaturated fats
Answer: C
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
39) Lipids found in the membranes of all eukaryotic cells are
A) polyunsaturated fats.
B) phospholipids.
C) steroids.
D) waxes.
E) triglycerides.
Answer: B
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
40) A protein is a __________ of amino acids.
A) monomer
B) polymer
C) bilayer
D) solution
E) decomposition product
Answer: B
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
11
Copyright © 2012 Pearson Education, Inc.
41) DNA is composed of repeating units of sugars, phosphates, and nucleic acids. This is an
example of a
A) polymer.
B) monomer.
C) salt.
D) micelle.
E) lipid.
Answer: A
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
42) A polymer composed of simple sugars is a(n)
A) protein.
B) triglyceride.
C) starch.
D) glycoprotein.
E) amino acid.
Answer: C
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
43) An amino acid is an example of a
A) monomer.
B) base.
C) micelle.
D) polymer.
E) salt.
Answer: A
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
44) Glucose is an example of what type of carbohydrate?
A) a disaccharide
B) a monomer
C) a pentose
D) a pentose polymer
E) a hexose monomer
Answer: E
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
12
Copyright © 2012 Pearson Education, Inc.
45) Adenosine triphosphate (ATP) is a
A) monomer.
B) polymer.
C) simple carbohydrate.
D) lipid.
E) bilayer.
Answer: A
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
46) Amylose is a(n) __________ carbohydrate.
A) simple
B) monomer
C) polymer
D) nucleotide
E) ionic
Answer: C
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
2.2 True/False Questions
1) The smallest chemical units of matter are elements.
Answer: FALSE
Bloom’s Rank: Knowledge
Section: Atoms
2) The side groups of amino acids can interact with each other and with other molecules.
Answer: TRUE
Bloom’s Rank: Comprehension
Section: Organic Molecules
3) Monosaccharides are usually found in cyclic forms.
Answer: TRUE
Bloom’s Rank: Comprehension
Section: Organic Molecules
4) The electron shells of atoms hold eight electrons each.
Answer: FALSE
Bloom’s Rank: Knowledge
Section: Atoms
5) Hydrogen bonds are stronger then covalent bonds.
Answer: FALSE
Bloom’s Rank: Comprehension
Section: Atoms
13
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6) Carbohydrates are composed of carbon, hydrogen, and oxygen.
Answer: TRUE
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
7) Denaturation of a protein is always permanent.
Answer: FALSE
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
8) The long-term chemical energy storage molecules in plants are triglycerides.
Answer: FALSE
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
9) One of the products of dehydration synthesis reactions is water.
Answer: TRUE
Bloom’s Rank: Knowledge
Section: Chemical Reactions
10) Salts are produced from exchange reactions in which acids and bases neutralize each other.
Answer: TRUE
Bloom’s Rank: Comprehension
Section: Water, Acids, Bases, and Salts
2.3 Short Answer Questions
1) Another name for a unit of atomic mass is a(n) __________.
Answer: dalton
Bloom’s Rank: Knowledge
Section: Atoms
2) Prokaryotes that grow best under acidic conditions are called __________.
Answer: acidophiles
Bloom’s Rank: Knowledge
Section: Water, Acids, Bases, and Salts
3) Cell surface markers composed of both carbohydrate and lipid molecules are known as
__________.
Answer: glycolipids
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
4) Molecules such as amino acids that have identical atoms and functional groups, but are mirror
images of each other, are __________.
Answer: stereoisomers
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
14
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5) A chemical reaction in which a water molecule is a reactant is known as a(n) __________
reaction.
Answer: hydrolysis
Bloom’s Rank: Comprehension
Section: Chemical Reactions
6) A(n) __________ is a molecule that binds with hydrogen ions when it is dissolved in water.
Answer: base
Bloom’s Rank: Knowledge
Section: Water, Acids, Bases, and Salts
7) The folding of a polypeptide into a three-dimensional shape is its __________ structure.
Answer: tertiary
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
8) The DNA double helix is held together by __________ bonds.
Answer: hydrogen
Bloom’s Rank: Knowledge
Section: Chemical Bonds
9) A six-carbon sugar is called a(n) __________.
Answer: hexose
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
10) A(n) __________ is any molecule that speeds up a chemical reaction.
Answer: catalyst
Bloom’s Rank: Comprehension
Section: Organic Macromolecules
11) The monomer of a nucleic acid is called a(n) __________.
Answer: nucleotide
Bloom’s Rank: Knowledge
Section: Organic Macromolecules
12) A chemical reaction that traps energy within newly formed chemical bonds is a(n)
__________ reaction.
Answer: endothermic
Bloom’s Rank: Knowledge
Section: Chemical Reactions
13) A(n) __________ is a substance that maintains the pH even when the amounts of acid and/or
base are changing.
Answer: buffer
Bloom’s Rank: Comprehension
Section: Water, Acids, Bases, and Salts
15
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14) The sum of all the chemical reactions within an organism is referred to as its __________.
Answer: metabolism
Bloom’s Rank: Knowledge
Section: Chemical Reactions
15) The __________ of an element vary in the number of neutrons in the nucleus.
Answer: isotopes
Bloom’s Rank: Knowledge
Section: Atoms
2.4 Essay Questions
1) Compare and contrast synthesis reactions with decomposition reactions.
Answer: Synthesis and decomposition reactions are often the reverse of each other. Synthesis
reactions consume energy (are endothermic), whereas decomposition reactions release energy
(are exothermic). Synthesis reactions often release water molecules in a process called
dehydration synthesis, whereas decomposition reactions often consume water molecules in a
process called hydrolysis. Finally, decomposition reactions break large macromolecules into
their component monomers, which can then be used in synthesis reactions to build new
macromolecules for use by the cell, whereas synthesis reactions utilize component monomers to
build larger molecules.
Bloom’s Rank: Application
Section: Chemical Reactions
2) Discuss the importance of hydrogen bonds in the chemistry of the cell.
Answer: The chemistry of the cell would basically be impossible without hydrogen bonds.
Water, which is required by all cellular reactions, would not have its unique properties of
cohesiveness and polarity without hydrogen bonds. Hydrogen bonds hold the double helix of
DNA together and contribute to the overall shape of protein molecules. However, unlike
covalent bonds, hydrogen bonds are not permanent bonds, so they can easily and temporarily be
broken, a characteristic that is important at certain points in the cell’s life cycle (such as during
DNA replication).
Bloom’s Rank: Application
Section: Chemical Bonds
3) Define and discuss the importance and impact of pH on living organisms.
Answer: pH is the measurement of the hydrogen ion concentration of a solution or within a cell.
The relationship between pH and hydrogen ions is an inverse one: as the number of hydrogen
ions increases, the pH drops (acid), and as the number of ions decreases, the pH rises (basic).
Changes in pH can have drastic consequences for important cellular molecules such as proteins,
which in turn can have a disastrous effect on the metabolism and structure of the cell; for this
reason, organisms can exist only in a fairly narrow range of pH. Although the range of pH that is
compatible with life is narrow, that range can vary widely among organisms: some organisms
prefer highly acidic pH levels, whereas others can function only at alkaline pH levels.
Bloom’s Rank: Application
Section: Water, Acids, Bases, and Salts
16
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4) Describe the chemical properties of phospholipids that account for their behavior in water.
Answer: Phospholipids have polar phosphate “heads” and nonpolar fatty acid “tails,” which
interact in different ways with water molecules. The phospholipid heads are attracted to polar
water molecules, but the nonpolar tails of the phospholipid are repelled by water. As the tails are
driven away from the water molecules, they congregate together, either in the interior of a ball of
lipid (called a micelle) or within the interior of a double layer of phospholipids (called a bilayer).
This leaves the phosphate heads “outside,” where they can easily interact with the water
molecules.
Bloom’s Rank: Application
Section: Organic Macromolecules
5) Nitrogen is an essential element for living things, as demonstrated by the fact that nearly all
fertilizers contain nitrogenous compounds. Discuss why nitrogen is essential.
Answer: Nitrogen is a component in the structure of two of the four types of organic
macromolecules. The amino group of an amino acid is a key reactant in the formation of peptide
bonds, or primary structure, of proteins. Nitrogen also participates in hydrogen bonding and
thereby contributes to the secondary, tertiary, and quaternary structure of proteins. Nitrogen is a
key structural component of the bases in nucleic acids, and its participation in hydrogen bonding
results in the formation of the base pairs and therefore the double helix of DNA.
Bloom’s Rank: Application
Section: Organic Macromolecules