Molecular Diagnosis : Fundamentals, Methods And Clinical Applications. 1st Edition Test Bank by Lela Buckingham, Maribeth L Flaws

Instant Download with all chapters and Answers

Sample Chapters

*you will get test bank in PDF in best viewable format after buy*

RNA

Page 1

1. The large ribosome subunit in prokaryotes consists of ribosomal proteins and:
A) 16S rRNA
B) 18S rRNA
C) 23S rRNA and 5S rRNA
D) 28S rRNA, 5S rRNA, and 5.8S rRNA
2. Messenger RNA is different from other types of RNA because messenger RNA has:
A) a 3 poly(A) tail
B) introns and exons
C) a 3 methylated cap
D) a cruciform structure
3. In an RNA molecule, adenine always base-pairs with:
A) thymine
B) cytosine
C) uracil
D) guanine
4. In transcription, what is the starting material, ending material, and the major enzyme that
catalyzes the process?
A) DNA, RNA, DNA polymerase
B) RNA, protein, peptidyl transferase
C) RNA, DNA, reverse transcriptase
D) DNA, RNA, RNA polymerase
5. If the following oligonucleotide of double-stranded DNA was transcribed, what would be the
sequence of the RNA?
5TGCTAGCTA3
3ACGATCGAT5
A) 5UGCUAGCUA3
B) 5ACGAUCGAU3
C) 3ACGATCGAT5
D) 3ACGAUCGAU5
6. Which of the following enzymes performs transcription in bacteria?
A) RNA-dependent DNA polymerase
B) DNA-dependent RNA polymerase
C) DNA-dependent DNA polymerase
D) RNA-dependent RNA polymerase

Chapter 2: RNA

Page 2

7. Which of the following types of RNA is directly involved in removing introns from RNA in
eukaryotes?
A) Micro
B) Transfer
C) Small nuclear
D) Small interfering
8. The loop of transfer RNA that interacts with the codon on mRNA in translation is called the:
A) D loop
B) TC loop
C) variable loop
D) anticodon loop
9. The RNA polymerase holoenzyme consists of which of the following?
A) 2,,
B) 2,,
C) ,,,
D) 2,,,
10. Which component of RNA polymerase is responsible for initiating transcription at the right
site?
A) 
B) 
C) 
D) 
E) 
11. DNA sequences that are involved in the regulation of gene expression are called:
A) cis factors
B) trans factors
C) attenuators
D) repressors
12. Which of the following is the binding site for the repressor protein of the lactose operon?
A) P site
B) Operator
C) A site
D) Promoter
13. Which of the following would prevent transcription of the lactose operon?
A) Loss of promoter
B) Presence of inducer
C) Loss of the repressor protein
D) RNA polymerase binding to the promoter

Chapter 2: RNA

Page 3

14. Which of the following is a cis factor of the lactose operon?
A) Inducer
B) Operator
C) Repressor
D) Polymerase
15. In the lactose operon, which of the following configurations would result in gene expression?
A) Promoter +, Operator +, Repressor +, no inducer present
B) Promoter -, Operator +, Repressor +, no inducer present
C) Promoter -, Operator -, Repressor +, inducer present
D) Promoter +, Operator +, Repressor -, no inducer present
16. Genomic imprinting is accomplished primarily through:
A) methylation
B) acetylation
C) transcription
D) cis and trans factor interactions
17. When gene expression is regulated by mechanisms other than the interaction of cis elements
and trans factors, the regulation is called:
A) induction
B) epigenetics
C) attenuation
D) combinatorial control
18. RNA and DNA are structurally similar because they both:
A) have ribose as their sugar moiety
B) consist of a single strand that folds on itself
C) consist of two complementary strands
D) are polymers of four different nucleotide bases
19. RNA is degraded by:
A) helicases
B) polymerases
C) ribonucleases
D) methylases

Chapter 2: RNA

Page 4

Answer Key
1. C
2. A
3. C
4. D
5. A
6. B
7. C
8. D
9. B
10. E
11. A
12. B
13. A
14. B
15. D
16. A
17. B
18. D
19. C